Guo-Yuan Yang Selected Research

Brain Infarction

6/2022	Blocking C3d+/GFAP+ A1 Astrocyte Conversion with Semaglutide Attenuates Blood-Brain Barrier Disruption in Mice after Ischemic Stroke.
2/2021	Transcranial Focused Ultrasound Stimulation Improves Neurorehabilitation after Middle Cerebral Artery Occlusion in Mice.
1/2020	Fingolimod Inhibits Inflammation but Exacerbates Brain Edema in the Acute Phases of Cerebral Ischemia in Diabetic Mice.
1/2020	MicroRNA-126-3p/-5p Overexpression Attenuates Blood-Brain Barrier Disruption in a Mouse Model of Middle Cerebral Artery Occlusion.
1/2019	L-glutamine protects mouse brain from ischemic injury via up-regulating heat shock protein 70.
11/2017	Endothelial progenitor cells transplantation attenuated blood-brain barrier damage after ischemia in diabetic mice via HIF-1α.
1/2017	Optogenetic Inhibition of Striatal Neuronal Activity Improves the Survival of Transplanted Neural Stem Cells and Neurological Outcomes after Ischemic Stroke in Mice.
12/2015	MicroRNA-29b is a therapeutic target in cerebral ischemia associated with aquaporin 4.
10/2014	Melatonin Pretreatment Improves the Survival and Function of Transplanted Mesenchymal Stem Cells after Focal Cerebral Ischemia.
7/2014	Neural stem cell protects aged rat brain from ischemia-reperfusion injury through neurogenesis and angiogenesis.

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Guo-Yuan Yang Research Topics

Disease

55	Ischemic Stroke 09/2022 - 04/2008
44	Brain Ischemia (Cerebral Ischemia) 01/2022 - 09/2003
38	Stroke (Strokes) 05/2022 - 04/2008
35	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2022 - 05/2002
34	Ischemia 06/2022 - 05/2002
27	Infarction (Infarctions) 01/2021 - 09/2003
26	Brain Injuries (Brain Injury) 12/2020 - 09/2003
14	Arteriovenous Malformations (Arteriovenous Malformation) 09/2017 - 04/2003
12	Brain Infarction 06/2022 - 03/2012
9	Hypoxia (Hypoxemia) 11/2017 - 04/2004
8	Atrophy 06/2022 - 04/2010
8	Inflammation (Inflammations) 12/2021 - 04/2004
8	Brain Edema (Cerebral Edema) 01/2020 - 12/2011
7	Cerebral Hemorrhage 01/2020 - 09/2007
7	Aneurysm (Aneurysms) 01/2018 - 06/2008
6	Edema (Dropsy) 09/2022 - 07/2013
6	Hemorrhage 02/2020 - 05/2005
5	Brain Diseases (Brain Disorder) 09/2022 - 01/2006
5	Vascular Diseases (Vascular Disease) 11/2017 - 08/2004
5	Neoplasms (Cancer) 01/2017 - 01/2003
4	Thrombosis (Thrombus) 09/2016 - 06/2008
3	Neuroinflammatory Diseases 06/2022 - 09/2018
3	Hypertension (High Blood Pressure) 12/2018 - 09/2006
3	Traumatic Brain Injuries (Traumatic Brain Injury) 12/2018 - 12/2011
3	Cerebral Infarction 01/2018 - 04/2008
3	Intracranial Aneurysm (Cerebral Aneurysm) 01/2018 - 06/2008
3	Hereditary Hemorrhagic Telangiectasia 09/2010 - 02/2004
3	Vascular Remodeling 07/2009 - 03/2007
3	Rupture 03/2009 - 09/2007
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 03/2009
2	Colorectal Neoplasms (Colorectal Cancer) 12/2021 - 12/2013
2	Pathologic Constriction (Stenosis) 02/2020 - 06/2008
2	Reperfusion Injury 10/2019 - 01/2018
2	Gliosis 10/2018 - 01/2017
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 05/2018 - 01/2016
2	Cognitive Dysfunction 01/2018 - 03/2010

Drug/Important Bio-Agent (IBA)

20	Proteins (Proteins, Gene)FDA Link 01/2021 - 05/2002
15	MicroRNAs (MicroRNA)IBA 06/2022 - 01/2011
13	Interleukin-6 (Interleukin 6)IBA 01/2020 - 01/2006
12	Biomarkers (Surrogate Marker)IBA 01/2019 - 03/2009
10	CytokinesIBA 01/2020 - 01/2004
9	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017 - 02/2004
7	Immunoglobulin G (IgG)IBA 09/2022 - 01/2013
6	Matrix Metalloproteinase 9 (Gelatinase B)IBA 09/2022 - 09/2006
6	Netrin-1IBA 12/2021 - 03/2011
6	erucylphosphocholineIBA 11/2017 - 04/2010
6	Matrix Metalloproteinases (MMPs)IBA 12/2011 - 04/2003
5	Neuroprotective AgentsIBA 09/2022 - 11/2017
5	Messenger RNA (mRNA)IBA 07/2019 - 01/2004
5	Caspase 3 (Caspase-3)IBA 05/2009 - 05/2002
4	Therapeutic UsesIBA 09/2022 - 01/2018
4	Tight Junction ProteinsIBA 01/2020 - 11/2017
4	Evans Blue (Blue, Evans)FDA Link 01/2020 - 12/2011
4	Pharmaceutical PreparationsIBA 01/2019 - 09/2014
4	methylarginyl- lysyl- prolyl- tryptophyl- tert- leucyl- leucyl- ethyl esterIBA 01/2016 - 03/2011
3	Interleukin-10 (Interleukin 10)IBA 02/2021 - 01/2015
3	Peroxidase (Myeloperoxidase)IBA 01/2020 - 06/2008
3	OccludinIBA 01/2020 - 01/2013
3	Sirolimus (Rapamycin)FDA Link 01/2019 - 02/2014
3	Aquaporin 4IBA 12/2018 - 12/2015
3	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 01/2006
3	Oxygen (Dioxygen)IBA 01/2018 - 01/2006
3	Insulin-Like Growth Factor I (IGF-1)IBA 01/2018 - 04/2008
3	Bromodeoxyuridine (BrdU)IBA 01/2017 - 10/2015
3	Interleukin-8 (Interleukin 8)IBA 10/2014 - 01/2013
3	EndoglinIBA 09/2010 - 02/2004
3	Activin Receptors (Activin Receptor)IBA 03/2009 - 02/2004
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2022 - 03/2009
2	CateninsIBA 01/2022 - 01/2020
2	Myelin Basic ProteinIBA 01/2022 - 10/2015
2	Erythropoietin FDA Link 01/2022 - 01/2016
2	Phosphotransferases (Kinase)IBA 12/2021 - 09/2010
2	Mitogen-Activated Protein Kinase 3IBA 01/2021 - 05/2002
2	p38 Mitogen-Activated Protein KinasesIBA 09/2020 - 12/2016
2	CalciumIBA 05/2020 - 04/2007
2	Streptozocin (Streptozotocin)FDA Link 01/2020 - 04/2016
2	VimentinIBA 01/2020 - 10/2018
2	EnzymesIBA 01/2020 - 09/2003
2	Tissue Plasminogen Activator (Alteplase)FDA Link 12/2019 - 01/2016
2	3-n-butylphthalide (butylphthalide)IBA 10/2019 - 01/2019
2	Hemoglobins (Hemoglobin)IBA 12/2017 - 11/2017
2	AdiponectinIBA 11/2017 - 12/2013
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 12/2016 - 01/2013
2	salicylhydroxamic acid (SHAM)IBA 08/2016 - 07/2008
2	Metformin (Glucophage)FDA LinkGeneric 10/2014 - 09/2014
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 10/2014 - 04/2004
2	MelatoninIBA 10/2014 - 01/2014
2	Green Fluorescent ProteinsIBA 10/2014 - 06/2014
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2014 - 04/2008
2	Insulin (Novolin)FDA Link 04/2014 - 04/2008
2	Adenosine Triphosphate (ATP)IBA 02/2014 - 04/2004

Therapy/Procedure

42	Therapeutics 05/2022 - 11/2004
20	Transplantation 01/2022 - 08/2005
9	Synchrotrons 12/2019 - 01/2012
7	Sutures (Suture) 09/2017 - 05/2009
5	Lasers (Laser) 01/2019 - 01/2011
3	Suture Techniques 04/2014 - 03/2012
2	Intravenous Injections 01/2022 - 01/2021
2	Injections 04/2017 - 12/2014
2	Microbubbles 09/2016 - 06/2011